A. Patents

“A. Τzakos, H. Stamatis , I. Gerotanasis, A, Cjatzikonstantinou,M. Chatziathanasiadou System and method for the production, characterization and biological evaluation of natural product analogues” Hellenic Industrial Property Organisation OBI-GREECE 1009100.

B. Publications in International Peer Reviewed Journals

​1) A. Xenakis, H. Stamatis, A. Malliaris, F.N. Kolisis. Effect of alcohols on the structure of AOT reverse micelles with respect to different enzyme activity. Progress in Colloid and Polymer Science, 93, 373-376, 1993. https://doi.org/10.1007/BFb0118630

2) H. Stamatis, A. Xenakis, M. Provelegiou F.N. Kolisis. Εsterification reactions catalyzed by lipases in microemulsions. The role of enzyme localiza­tion in relation to its selectivity. Biotechnology and Bioengineering, 42, 103-110, 1993. https://doi.org/10.1002/bit.260420114

3) H. Stamatis, F.N. Kolisis, A. Xenakis. Enantiomeric selectivity of a lipase from Penicillium simplicissimum in the esterification of menthol in microemulsions. Biotechnology Letters, 15 (5), 471-476, 1993. https://doi.org/10.1007/BF00129321

4) H. Stamatis, A. Xenakis, U. Menge and F.N. Kolisis. Kinetic study of lipase catalyzed esterification reactions in microemulsions. Biotechnology and Bioengineering, 42, 931-937, 1993. https://doi.org/10.1002/bit.260420803

5) H. Stamatis, F.N. Kolisis, A. Xenakis, U. Bornscheuer,T. Scheper, U. Menge. Pseudomonas cepacia lipase: Esterification reactions in AOT microemulsion systems. Biotechnology Letters 15(7), 703-708, 1993. https://doi.org/10.1007/BF01080143

6) U. Bornscheuer, H. Stamatis, A. Xenakis, T. Yamane, F.N. Kolisis. A comparison of different strate­gies for lipase-catalysed synthesis of partial glycerides. Biotechnology Letters 16, 697-702, 1994. https://doi.org/10.1007/BF00136474

7) H. Stamatis, A. Xenakis, F.N. Kolisis, A. Malliaris. Lipase localization in w/o microemulsions studied by fluorescence energy transfer. Progress in Colloid and Polymer Science, 97, 253-255, 1994 https://doi.org/10.1007/BFb0115178

8) H. Stamatis, A. Xenakis, E. Dimitriadis, F.N.Kolisis. Catalytic behavior of Pseudomonas cepacia lipase in w/o microemulsions. Biotechnology and Bioengineering, 45, 33-41, 1995. https://doi.org/10.1002/bit.260450106

9) H. Stamatis, A. Xenakis, F.N.Kolisis. Studies on enzyme reuse and product recovery in lipase catalyzed-reactions in microemulsions. Annals of the New York Academy of Science, 750, 237-241, 1995. https://doi.org/10.1111/j.1749-6632.1995.tb19958.x

10) A. Ballesteros, U. Bornscheuer, A. Capewell, D. Combes, J-S. Condoret, K. Koening, F.N. Kolisis, A. Marty, U. Menge, T. Scheper, H. Stamatis, Enzymes in non-conventional phases. – Review article Biocatalysis and Biotransformations, 13, 1-42, 1995. https://doi.org/10.3109/10242429509040103

11) J.B. Macris, H. Stamatis and F.N. Kolisis. Microemulsions as a tool for the regioselective lipase-catalysed esterifica­tion of aliphatic diols. Applied Microbiology and Biotechnology. 46, 521-524, 1996. https://doi.org/10.1007/s002530050854

12) V. Papadimitriou, A. Xenakis, C.T. Cazianis, H. Stamatis, M. Egmond. EPR studies of cutinase in microemulsions. Annals of the New York Academy of Science, 799, 275-280, 1996. https://doi.org/10.1111/j.1749-6632.1996.tb33213.x

13) H. Stamatis, J. Macris and F.N. Kolisis. Esterification of hydrophilic diols catalysed by lipases in microemulsions. Biotechnology Letters, 18, 541-546, 1996. https://doi.org/10.1007/BF00140200

14) S. Avramiotis, H. Stamatis, F.N. Kolisis, P. Lianos, A.Xenakis. Structural studies of lecithin and AOT-based water-in-oil microemulsions in the presence of lipase. Langmuir, 12, 6320-6328, 1996. https://doi.org/10.1021/la9606862

15) S. Avramiotis, H. Stamatis, F.N. Kolisis, A. Xenakis. Pseudomonas cepacia lipase localization in lecithin and AOT w/o microemulsions. A fluorescence energy transfer study. Progress in Colloid and Polymer Sci­ence, 105, 180-183, 1997. https://doi.org/10.1007/BFb0110984

16) V. Sereti, H. Stamatis, F.N. Kolisis. Improved stability and reactivity of Fusarium solani cutinase in supercritical CO2 Biotechnology Techniques 11, 661-665, 1997. https://doi.org/10.1023/A:1018407326284

17) C. Tsitsimpikou, H. Stamatis, V. Sereti, H. Daflos and F.N. Kolisis. Acylation of glucose catalysed by lipases in supercritical carbon dioxide. Journal of Chemical Technology and Biotechnology, 71, 309-314, 1998. https://doi.org/10.1002/(SICI)1097-4660(199804)71:4<309::AID-JCTB859>3.0.CO;2-L

18) H. Stamatis, P. Christakopoulos, D. Kekos, B.J. Makris, F.N. Kolisis. Studies on the synthesis of short-chain geranyl esters catalyzed by Fusarium oxysporum esterase in organic solvents. Journal of Molecular Catalysis B: Enzymatic, 4, 229-236, 1998. https://doi.org/10.1016/S1381-1177(98)00003-4

19) P. Christakopoulos, B. Tzalas, D. Mamma, H. Stamatis, Liadakis G.N., C. Tzia, D. Kekos, F.N. Kolisis, B.J. Makris. Production of an esterase from Fusarium oxysporum catalysing transesterification reactions in organic solvents. Process Biochemistry, 33(5), 585-594, 1998. https://doi.org/10.1016/S0032-9592(98)00039-9

20) H. Stamatis, V. Sereti and F.N. Kolisis. Studies on the enzymatic synthesis of sugar esters in organic medium and supercritical carbon dioxide. Chemical and Biochemical Engineering Quarterly, 12, 151-156, 1998. http://hdl.handle.net/123456789/12921

21) V. Sereti, H. Stamatis, E. Koukios and F.N. Kolisis. Enzymatic acylation of cellulose acetate in organic media. Journal of Biotechnology, 66, 219-223, 1998. https://doi.org/10.1016/S0168-1656(98)00085-6

22) H. Stamatis and A. Xenakis. Biocatalysis using microemulsion-based polymer gels containing immobilized lipase, Journal of Molecular Catalysis B: Enzymatic, 6, 399-406, 1999 https://doi.org/10.1016/S1381-1177(98)00142-8

23) Η. Stamatis, A. Xenakis, F.N. Kolisis, Bioorganic reactions in microemulsions: The case of lipase. Biotechnology Advances, 17(3), 293-318, 1999. (Invited paper) https://doi.org/10.1016/S0734-9750(99)00007-5

24) A. Xenakis and H. Stamatis. Lipase immobilization on microemulsion-based polymer gels. Progress in Colloid and Polymer Science, 112, 132-135, 1999 https://doi.org/10.1007/3-540-48953-3_28

25) H. Stamatis, V. Sereti and F.N. Kolisis. Studies on the enzymatic synthesis of lipophilic derivatives of natural antioxidants, Journal of the American Oil Chemist’s Society, 76(12), 1505-1510, 1999. https://doi.org/10.1007/s11746-999-0193-1

26) D.G. Hatzinikolaou, E. Kourentzi, H. Stamatis, P. Christakopoulos, F.N. Kolisis, D. Kekos and B.J. Makris. A novel lipolytic activity by Rhodotorula glutinis cells. Production, partial characterization and application in the synthesis of esters. Journal of Bioscience and Bioengineering, 88, 36-39, 1999. https://doi.org/10.1016/S1389-1723(99)80175-3

27) H. Stamatis, E.C.Voutsas, C. Delimitsou, F.N. Kolisis and D. Tassios. Enzymatic production of alkyl esters through lipase-catalyzed transesterification reactions in organic solvents: Solvent effect and prediction of equilibrium conversions. Biocatalysis and Biotransformation, 18, 259-269, 2000. https://doi.org/10.3109/10242420009015249

28) A. Pastou, H. Stamatis and A. Xenakis Microemulsion-based organogels containing lipase: Application in the synthesis of esters. Progress in Colloid and Polymer Science 115, 192-195, 2000 https://doi.org/10.1007/3-540-46545-6_39

29) H. Stamatis, V. Sereti and F.N. Kolisis. Enzymatic synthesis of hydrophilic and hydrophobic derivatives of natural phenolic acids in organic media. Journal of Molecular Catalysis B: Enzymatic 11, 323-328, 2001 https://doi.org/10.1016/S1381-1177(00)00016-3

30) V. Sereti, H. Stamatis, C. Pappas, M. Polissiou and F.N. Kolisis Enzymatic acylation of hydroxypropyl cellulose in organic media and determination of the ester formation by Diffuse Reflectance Infrared Fourier Transform (DRIFT) spectroscopy. Biotechnology and Bioengineering 72, 495-500, 2001 https://doi.org/10.1002/1097-0290(20010220)72:4<495::AID-BIT1012>3.0.CO;2-T

31) A. Kontogianni, V. Skouridou, V. Sereti, H. Stamatis and F.N. Kolisis. Regioselective acylation of flavonoids catalysed by lipase in non-toxic media. European Journal of Lipid Science and Technology, 103, 655-660, 2001. https://doi.org/10.1002/1438-9312(200110)103:10<655::AID-EJLT655>3.0.CO;2-X

32) E.C. Voutsas, H. Stamatis, F.N. Kolisis and D. Tassios. Solvent effect on equilibrium position and initial rate of lipase-catalyzed esterification reactions in organic solvents: Experimental results and prediction capabilities. Biocatalysis and Biotransformation, 20, 101-109, 2002. https://doi.org/10.1080/10242420290018087

33) Ch. Delimitsou, M. Zoumpanioti, A. Xenakis and H. Stamatis Activity and stability studies of Mucor miehei lipase immobilized in novel microemulsion-based organogels Biocatalysis and Biotransformation, 20, 319-327, 2002 https://doi.org/10.1080/10242420290025539

34) E. Franqueville, H. Stamatis, H. Loutrari, A. Friboulet, F.N. Kolisis. Studies on the catalytic behavior of a cholinesterase-like abzyme in an AOT microemulsion system Journal of Biotechnology, 97, 177-182, 2002. https://doi.org/10.1016/S0168-1656(02)00061-5

35) P. Christakopoulos, P. Katapodis, E. Kalogeris, D. Kekos, B.J. Macris, H. Stamatis, H. Skaltsa Antimicrobial activity of acidic xylo-oligosaccharides produced by family 10 and 11 endoxylanases. International Journal of Biological Macromolecules 31, 171-175, 2003 https://doi.org/10.1016/S0141-8130(02)00079-X

36) E., Topakas, H. Stamatis, P. Biely , D. Kekos, B.J. Macris , P. Christakopoulos, Purification and characterization of a feruloyl esterase from Fusarium oxysporum catalyzing esterification of phenolic acids in ternary water-organic solvent mixtures. Journal of Biotechnology, 102, 33-44, 2003 https://doi.org/10.1016/S0168-1656(02)00363-2

37) V. Skouridou, H. Stamatis and F.N. Kolisis Use of essential oils as media for the enantioselective esterification of the monoterpene perillyl alcohol catalyzed by lipase. European Journal of Lipid Science and Technology, 105 (3-4), 115-120, 2003. https://doi.org/10.1002/ejlt.200390026

38) E. Topakas, H. Stamatis, M. Mastihubova, P. Biely, D. Kekos, B.J. Macris, P. Christakopoulos Purification and characterization of a feruloyl esterase (FAE-I) from Fusarium oxysporum catalyzed transesterification of phenolic acid esters. Enzyme and Microbial Technology 33, 729-737, 2003. https://doi.org/10.1016/S0141-0229(03)00213-8

39) V. Skouridou, H. Stamatis and F.N. Kolisis. Lipase-mediated epoxidation of α-pinene. Journal of Molecular Catalysis B: Enzymatic, 21, 67-69, 2003 https://doi.org/10.1016/S1381-1177(02)00141-8

40) Y. Sanakis, D. Mamma, P. Christakopoulos, H. Stamatis Catechol 1,2-Dioxygenase from Pseudomonas putida in organic media – An Electron Paramagnetic Resonance study International Journal of Biological Macromolecules 33, 101-106, 2003 https://doi.org/10.1016/S0141-8130(03)00073-4

41) A. Kontogianni, V. Skouridou, V. Sereti, H. Stamatis and F.N. Kolisis. Lipase-catalyzed esterification of rutin and naringin with fatty acids of medium carbon. Journal of Molecular Catalysis B: Enzymatic, 21, 59-62, 2003. https://doi.org/10.1016/S1381-1177(02)00139-X

42) V. Skouridou, H. Stamatis and F.N. Kolisis. A study on the process of the lipase-catalyzed synthesis of α-pinene oxide in organic solvents. Biocatalysis and Biotransformation 21, 285-290, 2003 https://doi.org/10.1080/10242420310001597801

43) E. Franqueville, H. Loutrari, F. Mellou, H. Stamatis, A. Friboulet, F.N. Kolisis Reverse micelles, a system for antibody-catalysed reactions Journal of Molecular Catalysis B: Enzymatic 21 15-17, 2003 https://doi.org/10.1016/S1381-1177(02)00130-3

44) E. Topakas, H. Stamatis, P. Biely, P. Christakopoulos. Purification and characterization of a thermophilic feruloyl esterase from Sporotrichum thermophile (StFAE-A) catalyzing transesterification of phenolic acid esters. Applied Microbiology and Biotechnology 63(6), 686-690, 2004. https://doi.org/10.1007/s00253-003-1481-6

45) P. Dominguez de Maria, A. Xenakis, H. Stamatis, J. V. Sinisterra Lipase Factor (LF) as a characterization parameter to explain the catalytic activity of crude lipases from Candida rugosa, ATCC 14830, free or immobilized in microemulsion based organogels Enzyme and Microbial Technology 35 (4), 277-283, 2004. https://doi.org/10.1016/j.enzmictec.2003.10.018

46) V Skouridou, E.D. Chrysina, H. Stamatis, N. Oikonomakos, F. N. Kolisis Kinetic and modelling studies on the lipase catalysed enantioselective esterification of (±)-perillyl alcohol Journal of Molecular Catalysis B: Enzymatic, 29, 9-12, 2004. https://doi.org/10.1016/j.molcatb.2004.02.011

47) P. Dominguez de Maria, A. Xenakis, H. Stamatis, J. V. Sinisterra Unexpected reaction profile observed in the synthesis of propyl laurate when using Candida rugosa lipases immobilized in microemulsions based organogels. Biotechnology Letters, 26, 1517-1520, 2004. https://doi.org/10.1023/B:BILE.0000044455.42471.bf

48) M.Zoumpanioti, E.Karavas, C.Skopelitis, H.Stamatis, A. Xenakis. Lecithin organogels as model carriers of pharmaceuticals Progress in Colloid and Polymer Science, 123, 199-202, 2004. https://doi.org/10.1007/978-3-540-36462-7_44

49) F. Mellou, D. Lazari, H. Skaltsa, A.D. Tselepis, F.N. Kolisis, H. Stamatis Biocatalytic preparation of acylated derivatives of flavonoid glycosides enhances their antioxidant and antimicrobial activity Journal of Biotechnology, 116, 295-304, 2005 https://doi.org/10.1016/j.jbiotec.2004.12.002

50) E. Topakas, C. Vafiadi, H. Stamatis, P. Christakopoulos Sporotrichum thermophile type C feruloyl esterase (StFaeC): purification, characterization, and its use for phenolic acid (sugar) ester synthesis. Enzyme and Microbial Technology, 36, 729-736, 2005 https://doi.org/10.1016/j.enzmictec.2004.12.020

51) M. Zoumpanioti, M. Karali, A. Xenakis, H. Stamatis Lipase biocatalytic processes in surfactant free microemulsion – like ternary systems and related organogels, Enzyme and Microbial Technology, 39, 531-539, 2006 https://doi.org/10.1016/j.enzmictec.2005.03.030

52) E. Kalogeris, J. Sanakis, D. Mamma, P. Christakopoulos, D. Kekos, H. Stamatis Properties of catechol 1,2-dioxygenase from Pseudomonas putida immobilized in calcium alginate hydrogels, Enzyme and Microbial Technology, 39, 531-539, 2006 https://doi.org/10.1016/j.enzmictec.2006.02.026

53) M.H. Katsoura, A.C. Polydera, L. Tsironis, A.D. Tselepis, H. Stamatis Use of ionic liquids as media for the biocatalytic preparation of flavonoid derivatives with antioxidant potency Journal of Biotechnology 123, 491-503, 2006 https://doi.org/10.1016/j.jbiotec.2005.12.022

54) M. Zoumpanioti, H. Stamatis, V. Papadimitriou, A. Xenakis Catalytic and spectroscopic studies of lipases in ternary hexane-1-propanol-water microemulsion-like systems Colloids and Surfaces B: Biointerfaces 47, 1-9, 2006 https://doi.org/10.1016/j.colsurfb.2005.11.012

55) F. Mellou, H. Loutrari, H. Stamatis, C. Roussos, F. N. Kolisis Enzymatic esterification of flavonoids with unsaturated fatty acids. Effect of the novel esters on vascular endothelial growth factor release from K562 cells Process Biochemistry 41, 2029-2034, 2006 https://doi.org/10.1016/j.procbio.2006.05.002

56) M.H. Katsoura , A.C. Polydera, P. Katapodis, F.N. Kolisis, H. Stamatis Effect of different reaction parameters on the lipase-catalyzed selective acylation of polyhydroxylated natural compounds in ionic liquids. Process Biochemistry 2007 42, 1326-1334, 2007 https://doi.org/10.1016/j.procbio.2007.07.004

57) A. A. Tzialla, E. Kalogeris, D. Gournis, Y. Sanakis and H. Stamatis Enhanced catalytic performance and stability of chloroperoxidase from Caldariomyces fumago in surfactant free ternary water-organic solvent systems. Journal of Molecular Catalysis B: Enzymatic 51 (1-2), pp. 24-35, 2008 https://doi.org/10.1016/j.molcatb.2007.10.006

58) E. Serefoglou, K. Litina, D. Gournis, E. Kalogeris, A.A Tzialla, H. Stamatis, E.Maccallini, M. Lubomska, P. Rudolf. Smectite clays as solid supports for immobilization of β-glucosidase: Synthesis, Characterization and Biochemical properties Chemistry of Materials, 20 (12): 4106-4115, 2008 https://doi.org/10.1021/cm800486u

59) M. Zoumpanioti, P. Parmaklis, P. Dominguez de Maria, H. Stamatis, J.V. Sinisterra, A. Xenakis. Esterification reactions catalyzed by lipases immobilized in organogels. Effect of temperature and substrate diffusion Biotechnology Letters 30 (9), pp. 1627-1631, 2008 https://doi.org/10.1007/s10529-008-9734-1

60) E. Theodosiou, M. H. Katsoura, H. Loutrari, K. Purchartova, V. Kren, F.N. Kolisis H. Stamatis Enzymatic preparation of acylated derivatives of silybin in organic and ionic liquids media and evaluation of their anti-tumor proliferative activity Biocatalysis and Biotransformations 27(3): 161-169, 2009 https://doi.org/10.1080/10242420902937777

61) D. Mamma D. Hatzinikolaou D. Kekos, H. Stamatis E. Kalogeris, Adsorption of major endoglucanase from Thermoascus aurantiacus on cellulosic substrates World J Microbiol Biotechnol. 25 (5), pp. 781-788, 2009 https://doi.org/10.1007/s11274-008-9949-2

62) E. Xanthakis, S. Magkouta, H. Loutrari, H. Stamatis, C. Roussos, F.N. Kolisis Enzymatic synthesis of perillyl alcohol derivatives and investigation of their antiproliferative growth activity Biocatalysis and Biotransformation 27 (3), pp. 170-178, 2009 https://doi.org/10.1080/10242420902811089

63) I.V. Pavlidis, D. Gournis, G.K. Papadopoulos, H. Stamatis Lipases in Water-in-Ionic Liquid Microemulsions. Structural and Activity Studies Journal of Molecular Catalysis B: Enzymatic 60, 50–56, 2009 https://doi.org/10.1016/j.molcatb.2009.03.007

64) M. H. Katsoura, A. C. Polydera, L. D. Tsironis, M.P. Petraki, S. Kostić Rajačić, A. D. Tselepis H. Stamatis Efficient enzymatic preparation of hydroxycinnamates in ionic liquids enhances their antioxidant effect on lipoproteins oxidative modification New Biotechnology 26, 83-91, 2009 https://doi.org/10.1016/j.nbt.2009.02.004

65) A. A Tzialla, A.A. Taha, E. Kalogeris, H. Stamatis Improving the catalytic performance of fungal laccases in monoterpene-based reaction systems Biotechnology Letters, 31:1451–1456, 2009 https://doi.org/10.1007/s10529-009-0014-5

66) A. A Tzialla, E. Kalogeris, A. Enotiadis, A.A. Taha, D. Gournis, H. Stamatis Effective immobilization of Candida antarctica lipase B in organic-modified clays: Application for the epoxidation of terpenes. Materials Science and Engineering B 165 173–177, 2009 https://doi.org/10.1016/j.mseb.2009.09.003

67) A.A Tzialla, I.V. Pavlidis M Felicissimo, P. Rudolf, D. Gournis, H. Stamatis. Lipase immobilization on smectite nanoclays: Characterization and application to the epoxidation of α-pinene. Bioresource Technology 101 1587–1594, 2010 https://doi.org/10.1016/j.biortech.2009.10.023

68) M. Zoumpanioti, H. Stamatis, Microemulsion-based organogels as matrices for lipase immobilization Biotechnology Advances 28, 395–406, 2010 https://doi.org/10.1016/j.biotechadv.2010.02.004

69) E. Panteli, P. Saratsioti, H. Stamatis, E. Voutsas, “Solubilities of Cinnamic Acid Esters in Organic Solvents”, Journal of Chemical Engineering Data, 55 (2), pp. 745-749 2010. https://doi.org/10.1021/je9004382

70) E. Xanthakis, E. Theodosiou, S. Magkouta, H. Stamatis, H. Loutrari, C. Roussos, F.N Kolisis, Enzymatic Transformation of Flavonoids and Terpenoids: Structural and Functional Diversity of the Novel Derivatives. Pure and Applied Chemistry 82 (1), 1–16, 2010. https://doi.org/10.1351/PAC-CON-09-01-19

71) I.V. Pavlidis, T. Tsoufis, A. Enotiadis, D. Gournis, H. Stamatis Functionalized Multi-Wall Carbon Nanotubes for Lipase Immobilization. Advanced Engineering Materials 12 (5), pp. B179-B183, 2010 https://doi.org/10.1002/adem.200980021

72) Zoumpanioti M, Merianou E, Karandreas T, H. Stamatis, Xenakis A Esterification of phenolic acids catalyzed by lipases immobilized in organogels Biotechnology Letters 32 (10) 1457-1462 https://doi.org/10.1007/s10529-010-0305-x

73) I.V. Pavlidis, K. Tzafestas and H. Stamatis Water-in-ionic liquid microemulsions-based organogels as novel matrices for enzyme immobilization, Biotechnology Journal 5 (8), pp. 805-812, 2010 https://doi.org/10.1002/biot.201000052

74) Τheodosiou Ε., Loutrari, Η., Stamatis Η., Roussos C. Kolisis F., Biocatalytic synthesis and antitumor activities of novel silybin acylated derivatives with dicarboxylic acids New Biotechnology, 28 (4), pp. 342-348, 2011 https://doi.org/10.1016/j.nbt.2011.01.006

75) E. Kyriakou, A. Primikyri, P. Charisiadis, M. Katsoura, I. P. Gerothanassis, H. Stamatis, A. G. Tzakos Unexpected Enzyme-Catalyzed Regioselective Acylation of Flavonoid Aglycones and Rapid Product Screening. Organic Biomolecular Chemistry 10 (9), pp. 1739-1742,2012, DOI: 10.1039/C2OB06784F

76) A. Primikyri, E. Kyriakou, P. Charisiadis, C. Tsiafoulis, H. Stamatis A.G. Tzakos, I.P. Gerothanassis Fine-Tuning the Diffusion Dimension of -OH Groups for the Application of High Resolution DOSY in Mixture Analysis of Organic Compounds Tetrahedron 68 (34) , pp. 6887-6891 , 2012 https://doi.org/10.1016/j.tet.2012.06.016

77) I.V. Pavlidis, T. Vorhaben, T. Tsoufis, P. Rudolf, U.T. Bornscheuer, D. Gournis and H. Stamatis Development of effective nanobiocatalytic systems through the immobilization of hydrolases on functionalized carbon-based nanomaterials. Bioresource Technology 115 , pp. 164-171, 2012 https://doi.org/10.1016/j.biortech.2011.11.007

78) I.V. Pavlidis, T. Vorhaben, D. Gournis, G. K. Papadopoulos, U.T. Bornscheuer, and H. Stamatis Regulation of catalytic behavior of hydrolases through interactions with functionalized carbon-based nanomaterials. Journal of Nanoparticle Research 14 (5), art. no. 0842, 2012 https://doi.org/10.1007/s11051-012-0842-4

79) A.Taha, I. Shwaish, A.H Mohammed and H. Stamatis Production of a laccase from Botrytis cinerea (DSMZ 877) and application for textile phenolic dye decolorization Energy Procedia Journal 36, 862 – 871, 2013 https://doi.org/10.1016/j.egypro.2013.07.099

80) A.A. Papadopoulou, M.H. Katsoura, A. Chatzikonstantinou, E. Kyriakou, A.C. Polydera, A.G.Tzakos, H. Stamatis “Enzymatic hybridization of -lipoic acid with bioactive compounds in ionic solvents “Bioresourse Technology 136, 41–48, 2013 https://doi.org/10.1016/j.biortech.2013.02.067

81) M. Patila, I. Pavlidis, P. Katapodis, D. Gournis, H. Stamatis Enhancement of cytochrome c catalytic behaviour by affecting the heme environment using functionalized carbon-based nanomaterials Process Biochemistry 48, 1010–1017, 2013 https://doi.org/10.1016/j.procbio.2013.04.021

82) E. Theodosiou K. Purchartová H. Stamatis, F. Kolisis, V. Křen “Bioavailability of silymarin: Drug formulations and biotransformation“ Phytochemistry Reviews 13 (1), 1-18, 2014 https://doi.org/10.1007/s11101-013-9285-5

83) I V. Pavlidis, M. Patila, U.Τ. Bornscheuer, D. Gournis, H. Stamatis Graphene-based nanobiocatalytic systems: Recent advances and future prospects Trends in Biotechnology 32 (6), 312-320, 2014 https://doi.org/10.1016/j.tibtech.2014.04.004 (Invited paper)

84) Elena Geromichalou, Nisar Sayyad, Eleni Kyriakou, Alexandra Chatzikonstantinou, Efstathia Giannopoulou, Haralabos P. Kalofonos, Haralambos Stamatis, Andreas G. Tzakos Regioselective Chemical and Rapid Enzymatic Synthesis of a Novel Re-dox – Antiproliferative Molecular Hybrid” European Journal of Medicinal Chemistry 96, 47-57, 2015 https://doi.org/10.1016/j.ejmech.2015.03.064

85) Ali A. Taha, Nada Husham Abdulateef, Ghassaq Tariq Sadiq, Mohammed Omar Abdullatif, Haider Abdullzahra Glaiym, Haralambos Stamatis and Batol Imran Dheeb Laccase Production From Trametes hirsuta and Decolourisation of Phenolic Textile Dye In a Laccase Mediator System (LMS), Egypt. Acad. J. Biolog. Sci., 7(1): 19 – 27 (2015) http://microbiology.eajbs.eg.net/pdf/vol7.n1/3.pdf

86) Stelios Voulgaris, Athina A.Papadopoulou, Efthimia Alevizou, Haralambos Stamatis, Epaminondas VoutsasMeasurement and Prediction of Solvent Effect on Enzymatic Esterification Reactions Fluid Phase Equilibria 398, 51-62, 2015 https://doi.org/10.1016/j.fluid.2015.04.013

87) A. A. Papadopoulou, A. Tzani, D. Alivertis, M.H. Katsoura, A.C. Polydera, A. Detsi and H. Stamatis Hydroxyl ammonium ionic liquids as media for biocatalytic oxidations Green Chemistry, 18, 1147–1158, 2016 DOI: 10.1039/C5GC02381E

88) M. Patila, I.V. Pavlidis, A. Kouloumpis, K. Dimos, K. Spyrou, P. Katapodis, D. Gournis, H. Stamatis Graphene oxide derivatives with variable alkyl chain length and terminal functional groups as supports for stabilization of cytochrome c. International Journal of Biological Macromolecules, 84, 227–235, 2016. https://doi.org/10.1016/j.ijbiomac.2015.12.023

89) A.Giannakas, M.Vlacha, C. Salmasa, A. Leontiou, P. Katapodis, H. Stamatis, N-M. Barkoula, A. Ladavos Preparation, characterization, mechanical, barrier and antimicrobial properties of chitosan/PVOH/clay nanocomposites Carbohydrate Polymers 140, 408–415, 2016 https://doi.org/10.1016/j.carbpol.2015.12.072

90) M. Vlacha, A. Giannakas, P. Katapodis, H. Stamatis, A. Ladavos, N-M. Barkoula. On the efficiency of oleic acid as plasticizer of chitosan/clay nanocomposites and its role on thermo-mechanical, barrier and antimicrobial properties–comparison with glycerol Food Hydrocolloids 57, pp. 10-19, 2016 https://doi.org/10.1016/j.foodhyd.2016.01.003

91) A.Xenakis, M. Zoumpanioti, H. Stamatis Enzymatic reactions in structured surfactant-free microemulsions Opinion in Colloid and Interface Science 22, pp. 41-45, 2016 https://doi.org/10.1016/j.cocis.2016.02.009 (Invited paper)

92) M.Patila, A.Kouloumpis, D. Gournis, P. Rudolf, H.Stamatis Laccase-functionalized graphene oxide assemblies as efficient nanobiocatalysts for oxidation reactions Sensors, 2 16 (3), 287, 2016 https://doi.org/10.3390/s16030287

93) Α. Papadopoulou, Ε. Efstathiadou, Μ., Patila, Α., Polydera, Η., Stamatis Deep Eutectic Solvents as Media for Peroxidation Reactions Catalyzed by Heme-Dependent Biocatalysts Industrial & Engineering Chemistry Research 55 (18), pp. 5145-5151, 2016 https://doi.org/10.1021/acs.iecr.5b04867

94) A Papadopoulou, A. Tzani, A.C Polydera, P. Katapodis, E. Voutsas, A. Detsi, H. Stamatis Green biotransformations catalysed by enzyme-inorganic hybrid nanoflowers in environmentally friendly ionic solvents Environmental Science and Pollution Research International 1-8, 2017 DOI:10.1007/s11356-017-9271-3

95) A.V. Chatzikonstantinou, G-F Norra, H. Stamatis, E. Voutsas Prediction of Solvent Effect on Enzyme Enantioselectivity, Fluid Phase Equilibria 450, 126-132, 2017 https://doi.org/10.1016/j.fluid.2017.07.016

96) K. Khoshnevisan, F.Vakhshiteh, M. Barkhi, H. Baharifar, E. Poor-Akbar, N. Zari, H. Stamatis, Al-K Bordba Immobilization of cellulase enzyme onto magnetic nanoparticles: Applications and recent advances Molecular Catalysis 442, 66-73, 2017 https://doi.org/10.1016/j.mcat.2017.09.006

97) A. Chatzikonstantinou, M. Chatziathanasiadou, E. Ravera, M. Fragai, G. Parigi, I. Gerothanassis, C. Luchinat; H. Stamatis, A. Tzakos Enriching the biological space of natural products, through real time biotransformation monitoring: the NMR tube bioreactor BBA – General Subjects 1862 (1), 1-8, 2018 https://doi.org/10.1016/j.bbagen.2017.09.021

98) P. Zygouri, T. Tsoufis, A. Kouloumpis, M. Patila, G. Potsi, A.A. Sevastos, Z. Sideratou, F. Katsaros, G. Charalambopoulou, H. Stamatis, P. Rudolf, T. A. Steriotis D. Gournis Synthesis, characterization and assessment of hydrophilic oxidized carbon nanodiscs in bio-related applications RSC Advances, 8 (1), 122-131 2018 DOI: 10.1039/C7RA11045F

99) G. Orfanakis, M. Patila, A.V. Chatzikonstantinou, K-M. Lyra, A. Kouloumpis, P. Katapodis, K. Spyrou, A. Paipetis, P. Rudolf, D. Gournis, H. Stamatis Hybrid nanomaterials of magnetic iron nanoparticles and graphene oxide as matrices for the immobilization of ß-glucosidase: Synthesis, characterization and biocatalytic properties Frontiers in Materials, April 2018 | Volume 5 | Article 25, 1-15, 2018 https://doi.org/10.3389/fmats.2018.00025

100) M. Patila, E.K. Diamanti, D. Bergouni, A.C. Polydera, D. Gournis, H. Stamatis “Preparation and biochemical characterisation of nanoconjugates of functionalized carbon nanotubes and cytochrome c” Nanomedicine Research Journal 3 (1), 10-18, 2018 https://doi.org/10.3389/fmats.2018.00025

101) AV. Chatzikonstantinou, E. Gkantzou, D. Gournis, M. Patila, H. Stamatis Stabilization of laccase through immobilization on functionalized GO-derivatives Methods in Enzymology 48-80, 609, 2018 https://doi.org/10.1016/bs.mie2028.05.014 (Invited paper)

102) E. Gkantzou, M. Patila, H. Stamatis Magnetic microreactors with immobilized enzymes – from assemblage to contemporary applications Catalysts, 8, 282; 1-16, 2018 https://doi.org/10.3390/catal8070282 (Invited paper)

103) E. Mitsou, E. P Kalogianni, D. Georgiou, H. Stamatis, A. Xenakis, M. Zoumpanioti Formulation and Structural Study of a Biocompatible Water-in-Oil Microemulsion as an Appropriate Enzyme Carrier: The Model Case of Horseradish Peroxidase Langmuir, 35, 150-160, 2018 https://doi.org/10.1021/acs.langmuir.8b03124

104) P. Zygouri, T. Tsoufis, A. Kouloumpis, M. Patila, G. Potsi, Α. A. Sevastos, Z. Sideratou, F. Katsaros, G. Charalambopoulou, H. Stamatis, P. Rudolf, T. A. Steriotis, D. Gournis Synthesis, characterization and assessment of hydrophilic oxidized carbon nanodiscs in biorelated applications RSC Adv., 2018, 8, 122–131 DOI: 10.1039/C7RA11045F

105) D. Karageorgou, E. Thomou, N. T. Vourvou, K-M Lyra, N. Chalmpes, A. Enotiadis, K. Spyrou, P. Katapodis, D. Gournis, H. Stamatis Antibacterial and Algicidal Effects of Porous Carbon Cuboid 2 Nanoparticles, ACS Omega 4 (3), 4991-5001 2019 https://doi.org/10.1021/acsomega.8b02018

106) R. Fotiadou, M, Patila, M. Amen Hammami, A. Enotiadis, D. Moschovas, K. Tsirka, K. Spyrou, E. P. Giannelis, A. Avgeropoulos, A. Paipetis, D. Gournis, H. Stamatis Development of Effective Lipase-Hybrid Nanoflowers Enriched with Carbon and Magnetic Nanomaterials for Biocatalytic Transformations Nanomaterials 9 (6), 808, 2019 DOI: 10.3390/nano9060808 (Invited paper)

107) AV Chatzikonstantinou, E Gkantzou, E Thomou, N Chalmpes, KM Lyra, VG Kontogianni, K.Spyrou, M. Patila, D. Gournis, H. Stamatis Nanomaterials 9 (8), 1166, 2019 https://doi.org/10.3390/nano9081166 (Invited paper)

108) A. Giannakopoulou, E. Gkantzou, Α. Polydera and H. Stamatis Multienzymatic Nanoassemblies: Recent Progress and Applications Trends in Biotechnology https://doi.org/10.1016/j.tibtech.2019.07.010 (Invited paper)

109) A Papadopoulou, D Zarafeta, AP Galanopoulou, H Stamatis Enhanced Catalytic Performance of Trichoderma reesei Cellulase Immobilized on Magnetic Hierarchical Porous Carbon Nanoparticles The protein journal 38 (6), 640-648, 2019 https://doi.org/10.1007/s10930-019-09869-w

110) O. Boura-Theodoridou, A. Giannakas, P. Katapodis, H. Stamatis, A. Ladavos, N-M. Barkoula Performance of ZnO/chitosan nanocomposite films for antimicrobial packaging applications as a function of NaOH treatment and glycerol/PVOH blending Food Packaging and Shelf Life 23, 100456 https://doi.org/10.1016/j.fpsl.2019.100456

111) M Patila, N Chalmpes, E Dounousi, H Stamatis, D Gournis. Use of functionalized carbon nanotubes for the development of robust nanobiocatalysts Methods in Enzymology 630, 263-301 (Invited paper, in press) https://doi.org/10.1016/bs.mie.2019.10.015

112) A. Giannakopoulou, M. Patila, K. Spyrou, N. Chalmpes, D. Zarafeta, G. Skretas. D. Gournis and H. Stamatis Development of a Four-Enzyme Magnetic Nanobiocatalyst for Multi-Step Cascade Reactions, Catalysts 9(12), 995-1017; https://doi.org/10.3390/catal9120995 (Invited paper)
113) A.V Chatzikonstantinou, A.C. Polydera, E.Thomou, N. Chalmpes, T. N Baroud, A. Enotiadis, L. Estevez, M. Patila, M. A. Hammami, K. Spyrou, E. P. Giannelis, A. G. Tzakos, D. Gournis, H. Stamatis Bioresource Technology Reports 9, 100372 https://doi.org/10.1016/j.biteb.2019.100372
114. P. Koutsogiannis, E. Thomou, H. Stamatis, D. Gournis, P. Rudolf Advances in Fluorescent Carbon Dots for Biomedical Applications Advances in Physics 2020 (in press DOI: 10.1080/23746149.2020.1758592
115. P. Zygouri, K. Spyrou, E. Mitsari, M. Barrio, R. Macovez, M. Patila, H. Stamatis. I. I.Verginadis, A.P.Velalopoulou, A. M. Evangelou, Z. Sideratou, D. Gournis, P. Rudolf A facile approach to hydrophilic oxidized fullerenes and their derivatives as cytotoxic agents and supports for nanobiocatalytic systems 2020 (in press) Scientific Report, DOI : 10.1038/s41598-020-65117-7
116) Y. V Simos, K. Spyrou, M. Patila, N. Karouta, H. Stamatis, D. Gournis, E. Dounousi, D. Peschos Trends of nanotechnology in type 2 diabetes mellitus treatment Asian Journal of Pharmaceutical Sciences https://doi.org/10.1016/j.ajps.2020.05.001

C. Chapters in Books and Book Series (International Editions)

B1) H. Stamatis, A. Xenakis, H. Sztajer, U. Menge and F.N. Kolisis Studies on the specificity of Penicillium simplicissimum lipase catalyzed reactions in microemulsions. Progress in Biotechnology. Biocatalysis in Non-Conventional Media (Tramper et al. eds), Amsterdam, Elsevier, Vol. 8, pp.733-738, 1992, ΙSBN 0-444-89046-7. https://doi.org/10.1016/B978-0-444-89046-7.50105-3

B2). V. Sereti, H. Stamatis, F.N. Kolisis, Studies on the regioselective acylation of sugars catalyzed by lipase in tert-butanol. Progress in Biotechnology. (Ballesteros et al. Eds), Amsterdam Elsevier, Vol 15, pp.725-730, 1998 ΙSBN 0-444-50519-9. https://doi.org/10.1016/S0921-0423(98)80110-X

B3). V. Sereti, H. Stamatis, F.N. Kolisis. Strategies for the lipase-catalyzed regioselective acylation of polyols in organic media. Lipases and Lipids: Structure Function and Biotechnological Applications (G. Kokotos eds.), Cretan University Press, pp. 349-364, 2000 ISBN 960-524-111-0

B4) H. Stamatis, A. Xenakis and F.N. Kolisis. Synthesis of esters catalyzed by lipases in w/o microemulsions In: Methods in Biotechnology, Εnzymes in Nonaqueous Solvents, (Vulfson et al. Eds), Vol. 15, Chapter 28, Humana Press Inc. Totowa, NJ, pp. 331-338, 2001. ΙSBN 0-89603-929-3. https://doi.org/10.1385/1-59259-112-4:331

B5) H. Stamatis, V. Sereti and F.N. Kolisis. Lipase catalyzed synthesis of sugar fatty acid esters in supercritical carbon dioxide. In: Methods in Biotechnology, Εnzymes in Nonaqueous Solvents (Vulfson et al. Eds), Vol. 15, Chapter 39, Humana Press Inc, pp. 517-522, 2001, ΙSBN 0-89603-929-3 . https://doi.org/10.1385/1-59259-112-4:331

B6) M. H. Katsoura, E. Theodosiou, H. Stamatis F. N. Kolisis Strategies for the Biocatalytic Lipophilization of Phenolic Antioxidants In Modern biocatalysis, (Eds W-D Fessner, T Anthosen) Wiley 2009 pp. 323-333 ISBN: 978-3-527-62384-6

B7) A. Xenakis, V. Papadimitriou, H. Stamatis, F. N. Kolisis “Biocatalysis in microemulsuions” in “Microemulsions: Properties and Applications” Surfactant Sci.Ser., 2009, Vol.144, pp.349-385. Ed. M.Fanun., CRC Press, Jerusalem, Israel ISBN 9780367386214

B8) H Stamatis Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, 7 Volume Set Michael C. Flickinger (Editor) Wiley-VCH Verlag 2010, 44 pages ISBN: 978-0-471-79930-6

B9) I.V. Pavlidis, A.A. Tzialla, A.Enotiadis, D. Gournis, H. Stamatis Enzyme immobilization οn layered and nanostructured materials Ιn Biocatalysis in Polymer Chemistry, Edited by Katja Loos, Wiley-VCH Verlag & Co. KGaA, pp 35-64, 2010 ISBN: 978-3-527-32618-1 (Invited book chapter)

B10) I.V. Pavlidis, M. Patila, A. Polydera, D. Gournis, H. Stamatis Immobilisation of enzymes and other biomolecules In Functionalization of Graphene Editor: Vasilios Georgakilas, Wiley-VCH Verlag & Co, 2014, 35 pages DOI:10.1002/9783527672790 (Invited book chapter)

Β11) Μ. Katsoura, A. Papadopoulou A. Polydera, H. Stamatis Effect of ionic liquids on catalytic properties and structure of biocatalysts In Ionic Liquid-Based Surfactant Science: Formulation, Characterization, and Applications edited by Bidyut K. Paul and Satya P. Mouli Wiley-VCH Verlag & Co, 2015 ISBN: 978-1-118-83419-0 (Invited book chapter)

Β12 M. Patila, G. Orfanakis, A.C. Polydera, I.V. Pavlidis and H. Stamatis “Graphene-based Nanobiocatalytic Systems” Biocatalysis and Nanotechnology PanStanford Publishing, Singapore 2017 DOI: 10.4032/9781315196602 (Invited book chapter)

B13 E. M. Papamichael, H. Stamatis, P-Y. Stergiou, A. Foukis, O. A. Gkini Advances in Enzyme Technology Pages 71-104, 2019 https://doi.org/10.1016/B978-0-444-64114-4.00003-0